WU Bian 吴边

Dr. Bian Wu

  • Principal investigator, the Institute of Microbiology, Chinese Academy of Sciences

A principal investigator at the Institute of Microbiology, Chinese Academy of Sciences, is a recipient of the National Outstanding Young Scientists Award and serves as the chief investigator for the National Key Research and Development Program. He graduated with a degree in Pharmacy from Peking University in 2004 and earned his Ph.D. from the University of Groningen in the Netherlands in 2010. His primary research focuses on the field of microbial enzyme catalysis. In recent years, he has integrated protein computational design into enzyme engineering research. He has elucidated the detailed mechanisms of several types of microbial enzymes in catalyzing carbon-nitrogen bond formation and applied them to the precise synthesis and targeted modification of biomolecules through artificial modification. Wu Bian has published dozens of papers in prestigious academic journals such as Nature Catalysis and Nature Chemical Biology. Based on this work, he has developed a series of biosynthetic pathways for various chemicals, with several technologies like enzymatic peptide assembly, β-amino acid biosynthesis, and the sequential fermentation of heterocyclic drug intermediates successfully reaching industrial application. He has received multiple awards including the Hebei Province Science and Technology Progress First Prize and the Outstanding Young Enzyme Engineer Award from the Chinese Society for Microbiology. He currently serves as the drirector of the Enzyme Engineering Committee of the Chinese Society for Microbiology, and a council member of the China Synthetic Biology committee.